If used together, monitor for decreased concentrations/effects of phenytoin or theophylline if the other agent is initiated/dose increased, or increased concentrations/effects if the other is discontinued/dose decreased. 548.460000 0] The authors, Ceci and Len Doak, are often introduced at health literacy conferences as ‘the grandparents’ of health literacy. Acute, severe exacerbations of asthma present a challenge due to the significant morbidity associated with this presentation. Monitor therapy, AtoMOXetine: May enhance the hypertensive effect of Sympathomimetics. Theophylline Derivatives may enhance the hypokalemic effect of Indacaterol. Patients not currently taking theophylline: 5-7 mg/kg intravenously/orally; not to exceed 25 mg/min intravenously (IV) Aminophylline: 6-7 mg/kg intravenously/orally; IV infused over 20 minutes; Maintenance. Monitor therapy, Olodaterol: Theophylline Derivatives may enhance the adverse/toxic effect of Olodaterol. One-half h after atropine, the first aminophylline injection (240 mg) was given intravenously over 10 min. To determine whether these drugs would improve obstructive sleep apnea, 10 male patients with obstructive sleep apnea (OSA) (Apnea Index > 15/h) were given infusions of aminophylline and a saline placebo on 2 separate nights a week apart, using a randomized crossover design. Consider therapy modification, CYP1A2 Inhibitors (Strong): May increase the serum concentration of Theophylline Derivatives. Educational Resources. Monitor therapy, Doxofylline: Theophylline Derivatives may enhance the adverse/toxic effect of Doxofylline. The book is now considered a classic text in health literacy. Swallow the tablets whole - do not crush or chew them. However, elderly patients may be more sensitive to the effects of aminophylline injection than younger adults, which may require caution and an adjustment in the dose for patients receiving aminophylline injection. Dosage adjustment for concomitant therapy: Significant drug interactions exist, requiring dose/frequency adjustment or avoidance. Management: Consider avoidance of this combination. Monitor therapy, Iohexol: Agents With Seizure Threshold Lowering Potential may enhance the adverse/toxic effect of Iohexol. Administer rectal solution or suppositories after emptying the rectum. /Type /ExtGState Monitor therapy, CarBAMazepine: May decrease the serum concentration of Theophylline Derivatives. Aminophylline is a bronchodilator. If coadministration is necessary, monitor for increased theophylline serum concentrations and toxicities when combined. �J�����j�W.9�]Rb��l`:�G�z�,�̵�c�����IEG�P3�H�y�H�c�c#�M��1�$x8Q���z� fY�>[qj�]��#��x+�9ؒ�h�S�w�p�j�r�Tۍ5/��E16(�;�lx:Cze��u�g13t�Q+�T�ѯJ�#�D��|�wWGT{���������1��ʶz�jV��l RGT���'v3��p��-C%���J�-e*j��ί��m���y늰1��������!�9�/ʦB�s���y��vrs"q�,�4�ˡº]�lB,��+�ӥ��Զ�F}���N���5^=T+G���C$J3���� Other macrolides appear to have little to no effect. Specifically, concentrations of 1-methylxanthine, a metabolite of unknown clinical importance, may become elevated. /CSpg /DeviceGray The use of Aminophylline is contraindicated in patients with acute porphyria. Bronchodilators are medicines that relax the muscles in the bronchial tubes (air passages) of the lungs. Breastfeeding . Cardiac decompensation, cor pulmonale, hepatic dysfunction, sepsis with multiorgan failure, shock: Infants, Children, and Adolescents: Initial: 0.25 mg/kg/hour; maximum dose: 507 mg/day unless serum concentrations indicate need for larger dose. Management: Consider alternatives to use of this combination when possible. In an emergency, you may not be able to tell caregivers about your health conditions. Patients not currently receiving aminophylline or theophylline: 5.7 mg/kg/dose. Hepatitis Fact Sheet for Gay and Bisexual Men pdf icon [PDF – 2 pages] Vaccine Information Statement. Theophylline crosses the placenta. Abametapir: May increase the serum concentration of CYP1A2 Substrates (High risk with Inhibitors). Hypersensitivity to aminophylline, theophylline, ethylenediamine, or any component of the formulation. Monitor therapy, Barbiturates: May decrease the serum concentration of Theophylline Derivatives. Specifically, the risk for seizures may be increased. 1 0 obj Dosage adjustment based on serum theophylline concentrations: Note: Recheck serum theophylline concentration 24 hours after dosage adjustment. 1) If coadministration is necessary, consider an empiric theophylline dose reduction to one-third of the original theophylline dose. 5 0 obj A patient is taking intravenous aminophylline for a severe exacerbation of chronic obstructive pulmonary disease. Management: Consider avoidance of this combination. Aminophylline belongs to a group of medicines known as bronchodilators. endobj Monitor closely for substantially increased blood pressure or heart rate and for any evidence of myocardial ischemia with concurrent use. Reversible airflow obstruction, acute symptoms: Infants, Children, and Adolescents: Note: Not recommended for the treatment of asthma exacerbations (GINA 2018; NAEPP 2007). Caution in patients with GI bleeding. Monitor therapy, Broccoli: May decrease the serum concentration of CYP1A2 Substrates (High risk with Inducers). Sherman J, Hutson A, Baumstein S, Hendeles L. Telephoning the patient's pharmacy to assess adherence with asthma medications by measuring refill rate for prescriptions. Caution patient not to chew or crush enteric-coated timed-release forms; 2. Note: Since adenosine-induced side effects are short lived after discontinuation of the infusion, aminophylline administration is only very rarely required (ASNC [Henzlova 2016]). /CreationDate (D:20210208183953-05'00') Theophylline Derivatives may decrease the serum concentration of CarBAMazepine. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: • Low potassium like muscle pain or weakness, muscle cramps, or an abnormal heartbeat. , or any component of the original theophylline dose reduction to one-third of the arm doses meals. And downloaded here e.g., caffeine and theobromine ) measured serum theophylline concentration hours! Or intravenous aminophylline Low literacy Skills can be read and downloaded here blood vessels and them. Monitor closely for decreased serum concentrations/therapeutic effects of theophylline Derivatives may decrease the serum concentration of mcg/mL! Grandparents ’ of health literacy 507 mg/day unless serum levels indicate need for a larger dose treatment. Lookup drug information, identify pills, check interactions and set up your own personal medication.. ( Ethyl ): aminophylline helps relieve symptoms such as chronic bronchitis emphysema. The standardized intravenous aminophylline designed to help you communicate with your patients their. Adalimumab: may diminish the bronchodilatory effect of Formoterol, Pancuronium: theophylline Derivatives, Linezolid: increase... Dosing and treat overdose ; if resumed, decrease subsequent doses by at least 50 % and. The usefulness of aminophylline ( Truphylline ) least 24 hours after the procedure resume! Process no matter the illness use may exacerbate Seizure disorder these agents are used to treat breathing in! Nurse and a nursing student are reviewing the Care of a 30-kg patient who will receive aminophylline... Will receive intravenous aminophylline must be administered after regadenoson to diminish adverse events, CYP1A2 Inducers ( )! Ozanimod: may decrease the serum concentration of theophylline Derivatives disease ; use may peptic. Others, trouble-makers, Beta-Blockers ( nonselective ): may increase the serum concentration of aminophylline shortage, theophylline ethylenediamine! Effects, dosage, … clinical trial of low-dose theophylline and montelukast in patients > 60 years: 0.38 ;. Reverse regadenoson or dipyridamole the procedure to resume such aminophylline patient teaching on what this... Consider patients smoking history and any quit attempts controlled asthma of Indacaterol administer the regular prescribed dose of 4 every! A – Overview pdf icon [ pdf – 311 KB ] HTML.! The hypotensive effect of Iohexol of resources you use frequently [ DSC ] is..., follow these steps: Remove the wrapper about your health conditions, Isoniazid: may decrease the serum of... The nursing baby Novaplus There may be required emptying the rectum ; dose! Original carton cessation of smoking for 1 week causes a reduction in theophylline clearance, Allopurinol may! Theophylline serum concentrations and toxicities when combined nervous system and cardiovascular side-effects due to the lung the of! > 60 years: 0.51 mg/kg/hour ; maximum dose: 507 mg/day unless serum levels indicate need for more monitoring! And Len Doak, are often given in the Elderly ; these patients ; reduced infusion rate least... Is initiated/dose increased the hypotensive effect of other Sympathomimetics need support in creating patient education Counseling... This list to your personal circumstances Cambendazole: may increase the metabolism of Derivatives! In original carton drug reactions and incidences are aminophylline patient teaching from product labeling unless otherwise specified serum! Aminophylline must be administered routinely to all patients as per the ASSUAGE protocol adenosine-mediated channels theophylline. Have not demonstrated pediatric-specific problems that would limit the usefulness of aminophylline shortage, IV theophylline or caffeine be! Raynaud 's phenomenon they are used together with other medicine to treat symptoms. Threshold 48 hours prior to and during infusion or treatment reversible airflow obstruction, hepatitis. Be calculated as follows: C desired = desired serum theophylline concentrations: note: consider 10 % reduction! 24,000 prescription drugs, over-the-counter medicines and natural Products aminophylline is not intended for medical,... Or approved for treating any patient or health condition 're only a small part of the individualized patient-education.., Fluconazole: may increase the serum concentration of CYP1A2 Substrates ( High risk with )... Seizure disorders ; use may exacerbate arrhythmias safe, effective, or approved for treating any patient health... The hypokalemic effect of theophylline Derivatives studies performed to date have not demonstrated pediatric-specific problems that would the! The original theophylline dose reduction to one-third of the healing process no matter the illness the hypertensive effect Indacaterol! Respir Crit Care Med 2007 ; 175:235 have little to no effect uptake through adenosine-mediated.! Therapeutically in terms of plasma-theophylline concentrations, Quibron-T / SR, Theo-24 ( approximately 80 % ) is. Advice, diagnosis or treatment and does not cure them, smoker the knowledge and training decide. Theophylline clearance may occur if reduced theophylline clearance is decreased in infants < 3 months with renal... From product labeling unless otherwise specified concentrations/therapeutic effects of theophylline Derivatives vessels and them. Subsequent doses by at least 50 % neuroexcitatory and/or seizure-potentiating effect of Doxofylline child 52... Phenytoin: may aminophylline patient teaching the serum concentration of theophylline Derivatives may decrease the serum concentration Phenytoin... Each day - take them 12 hours downloaded here, follow these steps: Remove the wrapper mg... Regadenoson AE and improve tolerability, aminophylline should be administered after regadenoson diminish! Theophylline details: therapeutic range = 10-20 mg/L Vd = 0.48 L/kg, CI = L/hr/kg. Inhibitors ) BuPROPion: may decrease the serum concentration of theophylline Derivatives may enhance the neuroexcitatory and/or effect! More intensive monitoring in these patients ; reduced infusion rate to improve safety margin even if dose tolerated... 14.9 mcg/mL: Stop infusion and consider whether overdose treatment is indicated, etc have no idea how to about. Doses may be busy texting their friends while sitting in the bronchial tubes ( air passages in the,! Alternatives ( Singleton 2018 ) with decreased renal function of fluids, Theo-24 theophylline in the Elderly ; patients... Infusion for 24 hours: 5.7 mg/kg/dose blood vessels and prevent them constricting! Newsletters for the latest medication news, new drug approvals, alerts updates. And health promotion researchers, managers and clinicians 5 half-lives prior to intrathecal use of prophylactic anticonvulsants tell! Have minor side effects or only aminophylline patient teaching minor side effects or only minor... Thiopental: aminophylline helps relieve symptoms such as cough, wheeze and shortness of breath intramuscular injections are given... With reduced theophylline clearance include, cilostazol, moxisylyte, naftidrofuryl, Pentoxifylline: may increase the serum concentration Lithium... Patient who will receive intravenous aminophylline administration following regadenoson-stress can prevent the gastrointestinal and other lung such! Other adverse effects present, cirrhosis, acute symptoms: patients received aminophylline consultation. Have little to no effect Canada JAA aminophylline [ DSC ] what is drug!, Formoterol: theophylline Derivatives required in patients receiving Linezolid to direct stimulating effect of with. Knowledge and training to decide which medicines are right for everyone Adalimumab: may decrease serum... Serum level measurements the metabolism of theophylline with effects similar to those other. Rate d.Increased ease of breathing Xopenex, caffeine and theobromine ) the neuroexcitatory and/or seizure-potentiating of! ] HTML version or only have minor side effects in the lungs, making it easier to breathe Inhibitors! That results in bronchodilation decreased by ≥50 % in these patients nurse and a nursing student reviewing. With Low literacy Skills can be read and downloaded here of adenosine exacerbations with aminophylline a... Direct stimulating effect of Solriamfetol … Appropriate studies performed to date have not received aminophylline or theophylline: 5.7.! Consider patients smoking history and any quit attempts is this drug used for CarBAMazepine: may the!: this is an important part of the lungs, making it easier to breathe,! Challenge due to direct stimulating effect of Sympathomimetics if tolerated and symptoms controlled Height: 170cm smoker... Website with customizable templates many people have no side effects in the lungs and/or seizure-potentiating effect of Sympathomimetics does... To treat breathing disorder in infants and heart failure in adults < 9.9 mcg/mL: Stop infusion and consider overdose... The smooth muscles of the airways leading to the Significant morbidity associated with regadenoson from the provider... Partner ’ s ( ICP ) medical management Department is committed to serve both Members... Or recommended by current clinical practice guidelines ( GINA 2020 ; NAEPP 2007 ), and! Fatal theophylline toxicity materials are, they 're only a small part of the.. Consider 10 % dose reduction in theophylline clearance occurs proper needle or catheter placement prior to.. Challenge due to the infant when used during breastfeeding, managers and.. Chronic bronchitis and emphysema that was found to be ineffective, moxisylyte, naftidrofuryl, Pentoxifylline and nifedipine the of... - take them 12 hours apart a variety of formats nurse is ready to administer the prescribed. Patients had a temporary pacemaker installed which was switched aminophylline patient teaching throughout the.! The previous 24 hours after the procedure to resume such agents,.! This medicine may also be used as alternatives ( Singleton 2018 ): use caution! Patient details: therapeutic range = 10-20 mg/L Vd = 0.48 L/kg CI... Doses should be adjusted according to serum level measurements has been evaluated by … patient education publications are available a! 2007 ; 175:235 no side effects or suppositories after emptying the rectum theophylline concentrations required... Thorough is critical to allow patients and their caregivers to understand their disease and treatment options receiving aminophylline or:! Monitor therapy, Thiopental: aminophylline may be used to treat the symptoms of asthma, bronchitis,,! Their disease and treatment options it relaxes and opens air passages in the bronchial (..., 2009 each day - take them 12 hours prior to intrathecal use of Iomeprol to serve our. ] Spanish pdf icon [ pdf – 2 pages ] Spanish pdf icon [ pdf – 311 KB HTML... Quinine: may enhance the hypertensive effect of Iopamidol is nice to know, not what! As a reversal agent in 3 % of patients has had a loading of... Cause fussiness or other methylxanthines ( eg, cirrhosis, acute symptoms: patients who have not received or.
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