It is a dibasic acid, with pKas of 2.89 and 5.51. Data is generally displayed in milligram per kilo bodyweight. EC/LC50 for freshwater plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the freshwater plants in the test, generally displayed in milligram per litre. This section summarises the water solubility values from all registered dossiers for the substance. For example, substance impurities can constitute a valid reason for a different classification of the substance. For more information on total tonnage band calculation please consult the Data submission manual. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. Brief Profile - Last updated: 27/12/2020 Print. 2014 Jul;34(7):754-65. doi: 10.1002/jat.2902. This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Derived No- or Minimal Effect Level (DN(M)EL), Toxicokinetics, metabolism, and distribution, Endocrine disrupter mammalian screening - in vivo. 2005 Jun 1;210(2-3):223-33. Otherwise data is displayed reported as provided by the registrant(s). This section summarises the values related to toxicity to birds from all registered dossiers for the substance. Phthalic acid and isophthalic acid have protons on two carboxy groups that can be removed with base. Substances may have impurities and additives that lead to different classifications. Impurities or additives: When a specific critical property is associated with compositions with impurities and/or additives, the respective critical property icon has a * associated. Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure and closed batch processing in synthesis or formulation. This section summarises the values related to toxicity to aquatic algae and cyanobacteria from all registered dossiers for the substance. Values are generally displayed in milligram per litre. U.S. Patent US4734239, issued April, 1941. While the Agency tries to aggregate the information on chemicals in the best possible way, ECHA cannot check whether all the information provided by industry is free of errors. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. J Pharmacol Exp Ther. The availability of additional data beyond the five results displayed is indicated by (…) icon. This section provides an overview of the type of study records behind the presented results and data waving justifications. Phthalic acid {eq}(PH_2, PH^{-1}, P^{-2}) {/eq} is dibasic with pKa values of 2.95 and 5.41. Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions. For accuracy reasons, substance manufacturers and importers are responsible for consulting official sources. The information is aggregated from REACH registered dossiers provided by industry through a use descriptor system based on five separate descriptor lists which in combination with each other form a brief description of use and exposure for certain life cycle stage. Dossier evaluation – indicated if at least one registered dossier for the substance has been evaluated under REACH for compliance check or testing proposal evaluation and associated decision(s) published on the ECHA website. The dark blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in a REACH registration dossier. SMILES notations are comprised of atoms (designated by elemental symbols), bonds, parentheses (used to show branching), and numbers (used for cyclic structures). This section summarises the values related to adsorption/desorption from all registered dossiers for the substance. V.Care Service This section summarises the flash point values from all registered dossiers for the substance. The light blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in CLP notifications. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre. This section summarises the values related to phototransformation in water from all registered dossiers for the substance. Definitions of the acid dissociation constant and pKa are given below the figures, together with the definition of some classes of organic acids. References 1. the level of agreement, in substance classification between the REACH registrants (dark blue bar) and CLP notifiers (light blue bar), as well as between the notified classifications and the approved harmonised classification. The regulation aims improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemical industry. This section summarises the values related to long term toxicity to aquatic invertebrates from all registered dossiers for the substance. CAS names gives the name(s) provided to ECHA by the Chemical Abstracts Service, a division of the American Chemical Society, where available. Values are generally displayed in milligram per kilo food. Phthalic acid is an aromatic dicarboxylic acid,. Flash point provides substance information on the substance’s flash point at a temperature measured in °C at a pressure  measured in Pascal. - Mechanism of Action & Protocol. If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion. PNEC sediment, data displayed in milligram per kilo sediment (dry weight). 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